Deficiency of Stomach-Type Claudin-18 in Mice Induces Gastric Tumor Formation Independent of H pylori InfectionSummary

Deficiency of Stomach-Type Claudin-18 in Mice Induces Gastric Tumor Formation Independent of H pylori InfectionSummary

Background & Aims: Epithelial cells are joined by tight junctions (TJs) to form a cell sheet. In the stomach, epithelial cell sheet forms an essential barrier against gastric material, including gastric acid. Although the decreased expression of stomach-type claudin-18 (stCldn18), a TJ protein,...

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Bibliographic Details
Main Authors: Koya Suzuki, Kazuhiro Sentani, Hiroo Tanaka, Tomoki Yano, Kazuo Suzuki, Masanobu Oshima, Wataru Yasui, Atsushi Tamura, Sachiko Tsukita
Format: Article
Language:English
Published: Elsevier 2019-01-01
Series:Cellular and Molecular Gastroenterology and Hepatology
Online Access:http://www.sciencedirect.com/science/article/pii/S2352345X19300293

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http://www.sciencedirect.com/science/article/pii/S2352345X19300293

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