AGE-RELATED IMPAIRMENT OF PANCREATIC BETA-CELL FUNCTION: PATHOPHYSIOLOGICAL AND CELLULAR MECHANISMS.

The incidence of type 2 diabetes significantly increase with age. The relevance of this association is dramatically magnified by the concomitant global aging of the population, but the underlying mechanisms remain to be fully elucidated. Here some recent advances in this field are reviewed, at the l...

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Bibliographic Details
Main Author: Vincenzo eDe Tata
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-09-01
Series:Frontiers in Endocrinology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fendo.2014.00138/full