Effect of differential N-linked and O-linked mannosylation on recognition of fungal antigens by dendritic cells.

An experimental approach for improving vaccine efficacy involves targeting antigens to mannose receptors (MRs) on dendritic cells (DCs) and other professional antigen presenting cells. Previously, we demonstrated that mannosylated Pichia pastoris-derived recombinant proteins exhibited increased immu...

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Bibliographic Details
Main Authors: Jennifer S Lam, Haibin Huang, Stuart M Levitz
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-10-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC1995759?pdf=render