LncRNA NORAD promotes bone marrow stem cell differentiation and proliferation by targeting miR-26a-5p in steroid-induced osteonecrosis of the femoral head

LncRNA NORAD promotes bone marrow stem cell differentiation and proliferation by targeting miR-26a-5p in steroid-induced osteonecrosis of the femoral head

Abstract Background Steroid-induced osteonecrosis of the femoral head (SONFH) is a devastating orthopedic disease, which seriously affects the quality of life of patients. The study aims to investigate the effects of LncRNA NORAD on SONFH. Methods Human bone marrow-derived mesenchymal stem cells (hB...

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Bibliographic Details
Main Authors: Dapeng Fu, Sheng Yang, Jianmin Lu, Haoyi Lian, Kairong Qin
Format: Article
Language:English
Published: BMC 2021-01-01
Series:Stem Cell Research & Therapy
Subjects:
Steroid-induced osteonecrosis of the femoral head
LncRNA NORAD
miR-26a-5p
OPG/RANK/ RANKL pathway
Proliferation
Online Access:https://doi.org/10.1186/s13287-020-02075-x

Internet

https://doi.org/10.1186/s13287-020-02075-x

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