Integrative Pan-Cancer Analysis Reveals Decreased Melatonergic Gene Expression in Carcinogenesis and RORA as a Prognostic Marker for Hepatocellular Carcinoma

Integrative Pan-Cancer Analysis Reveals Decreased Melatonergic Gene Expression in Carcinogenesis and RORA as a Prognostic Marker for Hepatocellular Carcinoma

BackgroundMelatonin has been shown to play a protective role in the development and progression of cancer. However, the relationship between alterations in the melatonergic microenvironment and cancer development has remained unclear.MethodsWe performed a comprehensive investigation on 12 melatonerg...

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Bibliographic Details
Main Authors: Yi Zou, Huaqin Sun, Yating Guo, Yidan Shi, Zhiyu Jiang, Jingxuan Huang, Li Li, Fengle Jiang, Zeman Lin, Junling Wu, Ruixiang Zhou, Yuncai Liu, Lu Ao
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Oncology
Subjects:
melatonergic genes
pan-cancer analysis
expressional alteration
cancer occurrence and progression
prognosis
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.643983/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2021.643983/full

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