Polymorphism of the IL28B gene (rs8099917, rs12979860) and virological response of Pakistani hepatitis C virus genotype 3 patients to pegylated interferon therapy

Polymorphism of the IL28B gene (rs8099917, rs12979860) and virological response of Pakistani hepatitis C virus genotype 3 patients to pegylated interferon therapy

Background: The gold standard treatment for chronic hepatitis C virus (HCV) infection is pegylated interferon (PEG-IFN) in combination with ribavirin. Most patients treated with PEG-IFN achieve a sustained virological response (SVR). However host genetic factors play a vital role in the spontaneous...

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Bibliographic Details
Main Authors: Hafsa Aziz, Abida Raza, Khawar Ali, Jabar Zaman Khan Khattak, Javaid Irfan, Muzaffar Lateef Gill
Format: Article
Language:English
Published: Elsevier 2015-01-01
Series:International Journal of Infectious Diseases
Subjects:
IL28B
HCV genotype 3
PEG-IFN
Online Access:http://www.sciencedirect.com/science/article/pii/S1201971214017032

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http://www.sciencedirect.com/science/article/pii/S1201971214017032

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