Intravenous delivery of granulocyte-macrophage colony stimulating factor impairs survival in lipopolysaccharide-induced sepsis.

<h4>Background</h4>Cell-based therapies with bone marrow-derived progenitor cells (BMDPC) lead to an improved clinical outcome in animal sepsis models. In the present study we evaluated the ability of granulocyte macrophage-colony stimulating factor (GM-CSF) to mobilize BMDPC in a lipopo...

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Bibliographic Details
Main Authors: Jörg Krebs, Alexander Hillenbrand, Charalambos Tsagogiorgas, Christian Patry, Burkhard Tönshoff, Benito Yard, Grietje Beck, Neysan Rafat
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0218602