Transcriptome Changes in Three Brain Regions during Chronic Lithium Administration in the Rat Models of Mania and Depression

Transcriptome Changes in Three Brain Regions during Chronic Lithium Administration in the Rat Models of Mania and Depression

Lithium has been the most important mood stabilizer used for the treatment of bipolar disorder and prophylaxis of manic and depressive episodes. Despite long use in clinical practice, the exact molecular mechanisms of lithium are still not well identified. Previous experimental studies produced inco...

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Bibliographic Details
Main Authors: Dawid Szczepankiewicz, Piotr Celichowski, Paweł A. Kołodziejski, Ewa Pruszyńska-Oszmałek, Maciej Sassek, Przemysław Zakowicz, Ewa Banach, Wojciech Langwiński, Kosma Sakrajda, Joanna Nowakowska, Magdalena Socha, Ewelina Bukowska-Olech, Joanna Pawlak, Joanna Twarowska-Hauser, Leszek Nogowski, Janusz K. Rybakowski, Aleksandra Szczepankiewicz
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:International Journal of Molecular Sciences
Subjects:
manic-like behavior
depressive-like behavior
lithium
animal model
transcriptome
brain
Online Access:https://www.mdpi.com/1422-0067/22/3/1148

Internet

https://www.mdpi.com/1422-0067/22/3/1148

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