The paraventricular nucleus of the thalamus is recruited by both natural rewards and drugs of abuse: recent evidence of a pivotal role for orexin/hypocretin signaling in this thalamic nucleus in drug-seeking behavior

A major challenge for the successful treatment of drug addiction is the long-lasting susceptibility to relapse and multiple processes that have been implicated in the compulsion to resume drug intake during abstinence. Recently, the orexin/hypocretin (Orx/Hcrt) system has been shown to play a role i...

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Bibliographic Details
Main Authors: Alessandra eMatzeu, Eva Rebecca Zamora-Martinez, Remi eMartin-Fardon
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-04-01
Series:Frontiers in Behavioral Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnbeh.2014.00117/full