Development of a broad spectrum glycoconjugate vaccine to prevent wound and disseminated infections with Klebsiella pneumoniae and Pseudomonas aeruginosa.

Klebsiella pneumoniae (KP) and Pseudomonas aeruginosa (PA) are important human pathogens that are associated with a range of infection types, including wound and disseminated infections. Treatment has been complicated by rising rates of antimicrobial resistance. Immunoprophylactic strategies are not...

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Bibliographic Details
Main Authors: Nicolas Hegerle, Myeongjin Choi, James Sinclair, Mohammed N Amin, Morgane Ollivault-Shiflett, Brittany Curtis, Rachel S Laufer, Surekha Shridhar, Jerod Brammer, Franklin R Toapanta, Ian Alan Holder, Marcela F Pasetti, Andrew Lees, Sharon M Tennant, Alan S Cross, Raphael Simon
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6126813?pdf=render