Direct auditory cortical input to the lateral periaqueductal gray controls sound-driven defensive behavior.

Threatening sounds can elicit a series of defensive behavioral reactions in animals for survival, but the underlying neural substrates are not fully understood. Here, we demonstrate a previously unexplored neural pathway in mice that projects directly from the auditory cortex (ACx) to the lateral pe...

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Bibliographic Details
Main Authors: Haitao Wang, Jiahui Chen, Xiaotong Xu, Wen-Jian Sun, Xi Chen, Fei Zhao, Min-Hua Luo, Chunhua Liu, Yiping Guo, Wen Xie, Hui Zhong, Tongjian Bai, Yanghua Tian, Yu Mao, Chonghuan Ye, Wenjuan Tao, Jie Li, Zahra Farzinpour, Juan Li, Jiang-Ning Zhou, Kai Wang, Jufang He, Lin Chen, Zhi Zhang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-08-01
Series:PLoS Biology
Online Access:https://doi.org/10.1371/journal.pbio.3000417