Enhanced inhibition of tumor growth using TRAIL-overexpressing adipose-derived stem cells in combination with the chemotherapeutic agent CPT-11 in castration-resistant prostate cancer

Background: This study investigated the inhibition of tumor growth in castrate-resistant prostate cancer (CRPC)-bearing mice by tumor necrosis factor–related apoptosis-inducing ligand (TRAIL)-overexpressing adipose-derived stem cells (ADSCs) (hTERT-ADSC.sTRAIL), which was enhanced by combined treatm...

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Bibliographic Details
Main Authors: Jae Heon Kim, Eunjung Oh, Yong Seok Han, Sang Hun Lee, Yun Seob Song
Format: Article
Language:English
Published: Elsevier 2021-03-01
Series:Prostate International
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2287888220300489