An Integrative Pharmacology-Based Strategy to Uncover the Mechanism of Xiong-Pi-Fang in Treating Coronary Heart Disease with Depression

Objectives: This study aimed to explore the mechanism of Xiong-Pi-Fang (XPF) in the treatment of coronary heart disease (CHD) with depression by an integrative strategy combining serum pharmacochemistry, network pharmacology analysis, and experimental validation.Methods: An ultrahigh performance liq...

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Bibliographic Details
Main Authors: Lihong Zhang, Yu Zhang, Mingdan Zhu, Limin Pei, Fangjun Deng, JinHong Chen, Shaoqiang Zhang, Zidong Cong, Wuxun Du, Xuefeng Xiao
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.590602/full