Protein <i>O</i>-Fucosyltransferase 1 Undergoes Interdomain Flexibility in Solution

Protein <i>O</i>-Fucosyltransferase 1 Undergoes Interdomain Flexibility in Solution

Protein <i>O</i>-fucosyltransferase 1 (PoFUT1) is a GT-B fold enzyme that fucosylates proteins containing EGF-like repeats. GT-B glycosyltransferases have shown a remarkable grade of plasticity adopting closed and open conformations as a way of tuning their catalytic cycle, a feature tha...

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Bibliographic Details
Main Authors: Erandi Lira-Navarrete, María Carmen Pallarés, Fabio Castello, Maria J. Ruedas-Rama, Angel Orte, Anabel Lostao, Ramón Hurtado-Guerrero
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Molecules
Subjects:
glycosyltransferases
<i>O</i>-fucosylation
protein dynamics
atomic force microscopy
single-molecule methods
Online Access:https://www.mdpi.com/1420-3049/26/8/2105

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https://www.mdpi.com/1420-3049/26/8/2105

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