Human Pancreatic Islets Transfected to Produce an Inhibitor of TNF are Protected against Destruction by Human Leukocytes

The objective of this study was to determine whether transfection of human islets with an adenovirus construct encoding an inhibitor of tumor necrosis factor (TNFi) was effective at limiting damage to beta cells induced by human peripheral blood leukocytes (huPBL). Human islets transfected with TNFi...

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Bibliographic Details
Main Authors: Trey Dobson, Dan Fraga, Corey Saba, Michael Bryer-Ash, A. Osama Gaber, Ivan C. Gerling Ph.D.
Format: Article
Language:English
Published: SAGE Publishing 2000-11-01
Series:Cell Transplantation
Online Access:https://doi.org/10.1177/096368970000900612