Neuroprotective Effects of Pre-Treament with l-Carnitine and Acetyl-l-Carnitine on Ischemic Injury In Vivo and In Vitro

Neuroprotective Effects of Pre-Treament with l-Carnitine and Acetyl-l-Carnitine on Ischemic Injury In Vivo and In Vitro

The therapeutic effect of stroke is hampered by the lack of neuroprotective drugs against ischemic insults beyond the acute phase. Carnitine plays important roles in mitochondrial metabolism and in modulating the ratio of coenzyme A (CoA)/acyl-CoA. Here, we investigate the neuroprotective effects of...

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Bibliographic Details
Main Authors: Shunjiang Xu, Tao Wang, Jingya Niu, Dongsheng Cui, Zhongxia Zhang, Hong Zhang, Rui Zhang
Format: Article
Language:English
Published: MDPI AG 2012-02-01
Series:International Journal of Molecular Sciences
Subjects:
ischemia
l-carnitine
Acetyl-l-carnitine
neuroprotection
oxygen-glucose deprivation
Online Access:http://www.mdpi.com/1422-0067/13/2/2078/

Internet

http://www.mdpi.com/1422-0067/13/2/2078/

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