Investigating BB0405 as a novel Borrelia afzelii vaccination candidate in Lyme borreliosis

Abstract BB0405 is a surface exposed Borrelia burgdorferi protein and its vaccination protected mice against B. burgdorferi infection. As BB0405 is highly conserved across different B. burgdorferi sensu lato species, we investigated whether vaccination with recombinant BB0405 or through intradermal...

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Bibliographic Details
Main Authors: M. J. Klouwens, J. J. Trentelman, J. I. Ersoz, F. Nieves Marques Porto, R. Sima, O. Hajdusek, M. Thakur, U. Pal, J. W. Hovius
Format: Article
Language:English
Published: Nature Publishing Group 2021-02-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-84130-y