Response prediction in chronic hepatitis C by assessment of IP-10 and IL28B-related single nucleotide polymorphisms.

BACKGROUND:High baseline levels of IP-10 predict a slower first phase decline in HCV RNA and a poor outcome following interferon/ribavirin therapy in patients with chronic hepatitis C. Several recent studies report that single nucleotide polymorphisms (SNPs) adjacent to IL28B predict spontaneous res...

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Bibliographic Details
Main Authors: Martin Lagging, Galia Askarieh, Francesco Negro, Stephanie Bibert, Jonas Söderholm, Johan Westin, Magnus Lindh, Ana Romero, Gabriele Missale, Carlo Ferrari, Avidan U Neumann, Jean-Michel Pawlotsky, Bart L Haagmans, Stefan Zeuzem, Pierre-Yves Bochud, Kristoffer Hellstrand, DITTO-HCV Study Group
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-02-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3044738?pdf=render