Application of Epstein–Barr Virus for Optimization of Immortalized B-lymphocyte Production as a Positive Control in Genetic Studies

Application of Epstein–Barr Virus for Optimization of Immortalized B-lymphocyte Production as a Positive Control in Genetic Studies

Background: Infection of B-cells with Epstein–Barr virus (EBV) leads to more and subsequent immortalization. This is considered as the method of choice for generating lymphoblastoid cell lines (LCLs). Producing LCLs, although very useful but is very time consuming and troublesome, drives the require...

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Bibliographic Details
Main Authors: Behnaz Tousizadeh, Sharareh Moghim, Ahmad Reza Salehi Chaleshtori, Maryam Ghanbarian, Mina Mirian, Mansoor Salehi, Sepideh Tousizadeh, Fatemeh Zaboli
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2017-01-01
Series:Advanced Biomedical Research
Subjects:
B95 cell
Epstein–Barr virus
immortalization
lymphoblastoids cell line
optimization
Online Access:http://www.advbiores.net/article.asp?issn=2277-9175;year=2017;volume=6;issue=1;spage=80;epage=80;aulast=Tousizadeh

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http://www.advbiores.net/article.asp?issn=2277-9175;year=2017;volume=6;issue=1;spage=80;epage=80;aulast=Tousizadeh

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