Prestin regulation and function in residual outer hair cells after noise-induced hearing loss.

The outer hair cell (OHC) motor protein prestin is necessary for electromotility, which drives cochlear amplification and produces exquisitely sharp frequency tuning. Tecta(C1509G) transgenic mice have hearing loss, and surprisingly have increased OHC prestin levels. We hypothesized, therefore, that...

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Bibliographic Details
Main Authors: Anping Xia, Yohan Song, Rosalie Wang, Simon S Gao, Will Clifton, Patrick Raphael, Sung-il Chao, Fred A Pereira, Andrew K Groves, John S Oghalai
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3869702?pdf=render