Pulp stem cells with hepatocyte growth factor overexpression exhibit dual effects in rheumatoid arthritis

Pulp stem cells with hepatocyte growth factor overexpression exhibit dual effects in rheumatoid arthritis

Abstract Background To investigate the therapeutic effect of human dental pulp stem cells (DPSCs) transfected with adenovirus expressing hepatocyte growth factor (HGF) in a mouse model of collagen-induced arthritis (CIA). Methods DPSCs were modified with Ad-HGF to produce HGF-overexpressing DPSCs, D...

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Bibliographic Details
Main Authors: Xiwen Dong, Fanxuan Kong, Chao Liu, Shiyun Dai, Yuning Zhang, Fengjun Xiao, Huan Zhang, Chu-Tse Wu, Hua Wang
Format: Article
Language:English
Published: BMC 2020-06-01
Series:Stem Cell Research & Therapy
Subjects:
Dental pulp stem cells (DPSCs)
Hepatocyte growth factor (HGF)
Rheumatoid arthritis (RA)
Cell therapy
Online Access:http://link.springer.com/article/10.1186/s13287-020-01747-y

Internet

http://link.springer.com/article/10.1186/s13287-020-01747-y

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