Pulp stem cells with hepatocyte growth factor overexpression exhibit dual effects in rheumatoid arthritis
Abstract Background To investigate the therapeutic effect of human dental pulp stem cells (DPSCs) transfected with adenovirus expressing hepatocyte growth factor (HGF) in a mouse model of collagen-induced arthritis (CIA). Methods DPSCs were modified with Ad-HGF to produce HGF-overexpressing DPSCs, D...
Main Authors: | , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2020-06-01
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Series: | Stem Cell Research & Therapy |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s13287-020-01747-y |