Vacuolar ATPase depletion contributes to dysregulation of endocytosis in bloodstream forms of Trypanosoma brucei
Abstract Background Vacuolar H+-ATPase (V-ATPase) is a highly conserved protein complex which hydrolyzes ATP and pumps protons to acidify vacuolar vesicles. Beyond its role in pH maintenance, the involvement of V-ATPase in endocytosis is well documented in mammals and plants but is less clear in Try...
Main Authors: | Zhi-Shen Xu, Feng-Jun Li, Geoff Hide, Zhao-Rong Lun, De-Hua Lai |
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Format: | Article |
Language: | English |
Published: |
BMC
2020-04-01
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Series: | Parasites & Vectors |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s13071-020-04068-4 |
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