Enhanced MRI T 2 Relaxivity in Contrast-Probed Anchor-Free PEGylated Iron Oxide Nanoparticles

Enhanced MRI T 2 Relaxivity in Contrast-Probed Anchor-Free PEGylated Iron Oxide Nanoparticles

Abstract Superparamagnetic iron oxide nanoparticles (SPIONs, ~11-nm cores) were PEGylated without anchoring groups and studied as efficient MRI T 2 contrast agents (CAs). The ether group of PEG is efficiently and directly linked to the positively charged surface of SPIONs, and mediated through a dip...

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Bibliographic Details
Main Authors: Bibek Thapa, Daysi Diaz-Diestra, Juan Beltran-Huarac, Brad R. Weiner, Gerardo Morell
Format: Article
Language:English
Published: SpringerOpen 2017-04-01
Series:Nanoscale Research Letters
Subjects:
PEGylation
Magnetic iron oxide nanopaticles
T 2 relaxivity
MRI contrast agents
Online Access:http://link.springer.com/article/10.1186/s11671-017-2084-y

Internet

http://link.springer.com/article/10.1186/s11671-017-2084-y

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