The c-Met receptor tyrosine kinase inhibitor MP470 radiosensitizes glioblastoma cells

<p>Abstract</p> <p>Purpose</p> <p>Glioblastoma multiforme (GBM) is resistant to current cytotoxic therapies, in part because of enhanced DNA repair. Activation of the receptor tyrosine kinase c-Met has been shown to protect cancer cells from DNA damage. We hypothesized...

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Bibliographic Details
Main Authors: Bearss David, Cooke Laurence, Ellsworth Ron, Mahadevan Daruka, Welsh James W, Stea Baldassarre
Format: Article
Language:English
Published: BMC 2009-12-01
Series:Radiation Oncology
Online Access:http://www.ro-journal.com/content/4/1/69