Bone formation with functionalized 3D printed poly-ε-caprolactone scaffold with plasma-rich-fibrin implanted in critical-sized calvaria defect of rat

Background/purpose: Space-making is one of the essential factors for bone regeneration in severe bony defect. To test the hypothesis that an appropriately designed scaffold may be beneficial for the bone formation in defect, the new bone formed in the critical-size calvarial defect of rat was examin...

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Bibliographic Details
Main Authors: Min-Chia Chen, Hsien-Chung Chiu, Po-Jan Kuo, Cheng-Yang Chiang, Martin M. Fu, Earl Fu
Format: Article
Language:English
Published: Elsevier 2021-10-01
Series:Journal of Dental Sciences
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1991790221000209