Tubeimoside I Protects Dopaminergic Neurons Against Inflammation-Mediated Damage in Lipopolysaccharide (LPS)-Evoked Model of Parkinson’s Disease in Rats

Tubeimoside I Protects Dopaminergic Neurons Against Inflammation-Mediated Damage in Lipopolysaccharide (LPS)-Evoked Model of Parkinson’s Disease in Rats

Parkinson’s disease (PD), a frequent degenerative disease in the elderly, is characterized by dopaminergic neurodegeneration in the substantia nigra pars compacta (SNpc). Neuroinflammation caused by over-activated microglia plays a crucial role in the pathogenesis of PD. Tubeimoside I (TBM...

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Bibliographic Details
Main Authors: Dewei He, Bingxu Huang, Shoupeng Fu, Yuhang Li, Xin Ran, Yandan Liu, Guangxin Chen, Juxiong Liu, Dianfeng Liu
Format: Article
Language:English
Published: MDPI AG 2018-07-01
Series:International Journal of Molecular Sciences
Subjects:
Tubeimoside I
microglia
Parkinson’s disease
MAPKs
NF-κB
Online Access:http://www.mdpi.com/1422-0067/19/8/2242

Internet

http://www.mdpi.com/1422-0067/19/8/2242

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