Saikosaponin D inhibits proliferation and promotes apoptosis in breast cancer cells through down-regulating JAK2/STAT3 pathway

Saikosaponin D inhibits proliferation and promotes apoptosis in breast cancer cells through down-regulating JAK2/STAT3 pathway

Objective To investigate the effect of saikosaponin D on the proliferation and apoptosis of breast cancer MCF-7 cells by JAK2/STAT3 pathway. Methods The breast cancer MCF-7 cells were divided into control group, low-dose group, middle-dose, and high-dose groups (treated with 0, 5, 10 and 20 μmol/L s...

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Bibliographic Details
Main Authors: FENG Jiexin, WU Xiong, CHEN Jianhui, LIN Qinghai, YE Zelin
Format: Article
Language:zho
Published: Editorial Office of Journal of Third Military Medical University 2021-05-01
Series:Di-san junyi daxue xuebao
Subjects:
saikosaponin d
jak2/stat3 pathway
breast cancer
mcf-7 cells
proliferation
apoptosis
Online Access:http://aammt.tmmu.edu.cn/Upload/rhtml/202010217.htm

Internet

http://aammt.tmmu.edu.cn/Upload/rhtml/202010217.htm

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