A Novel Calcium Uptake Transporter of Uncharacterized P-Type ATPase Family Supplies Calcium for Cell Surface Integrity in Mycobacterium smegmatis

Ca2+ plays an important role in the physiology of bacteria. Intracellular Ca2+ concentrations are tightly maintained in the nanomolar range. Molecular mechanisms of Ca2+ uptake in bacteria remain elusive. Here we show that CtpE is responsible for Ca2+ uptake in Mycobacterium smegmatis. It represents...

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Bibliographic Details
Main Authors: Hemant Kumar Gupta, Shruti Shrivastava, Rakesh Sharma, Gloria Marcela Rodriguez, Eric J. Rubin
Format: Article
Language:English
Published: American Society for Microbiology 2017-09-01
Series:mBio
Online Access:http://mbio.asm.org/cgi/content/full/8/5/e01388-17