Tamsulosin Associated with Interstitial Lung Damage in CYP2D6 Variant Alleles Carriers

Tamsulosin Associated with Interstitial Lung Damage in CYP2D6 Variant Alleles Carriers

Drugs are serious but underestimated causative agents of interstitial lung disease (ILD). Both cytotoxic and immune mechanisms may be involved in drug-induced ILD (DI-ILD). We aimed to investigate whether polymorphisms of relevant CYP enzymes involved in the metabolization of tamsulosin might explai...

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Bibliographic Details
Main Authors: Naomi T. Jessurun, Petal A. Wijnen, Aalt Bast, Eugène P. van Puijenbroek, Otto Bekers, Marjolein Drent
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:International Journal of Molecular Sciences
Subjects:
tamsulosin
drug-induced interstitial lung disease
pharmacogenetics
CYP2D6
CYP3A4/5
drug metabolizing enzymes
Online Access:https://www.mdpi.com/1422-0067/21/8/2770

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https://www.mdpi.com/1422-0067/21/8/2770

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