On the hepatic mechanism of HDL assembly by the ABCA1/apoA-I pathway

On the hepatic mechanism of HDL assembly by the ABCA1/apoA-I pathway

The mechanism for the assembly of HDL with cellular lipid by ABCA1 and helical apolipoprotein was investigated in hepatocytes. Both HepG2 cells and mouse primary culture hepatocytes produced HDL with apolipoprotein A-I (apoA-I) whether endogenously synthesized or exogenously provided. Probucol, an A...

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Bibliographic Details
Main Authors: Maki Tsujita, Cheng-Ai Wu, Sumiko Abe-Dohmae, Shinichi Usui, Mitsuyo Okazaki, Shinji Yokoyama
Format: Article
Language:English
Published: Elsevier 2005-01-01
Series:Journal of Lipid Research
Subjects:
cholesterol
high density lipoprotein
hepatocytes
HepG2
probucol
apolipoprotein A-I
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520340918

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http://www.sciencedirect.com/science/article/pii/S0022227520340918

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