DENV inhibits type I IFN production in infected cells by cleaving human STING.

DENV inhibits type I IFN production in infected cells by cleaving human STING.

Dengue virus (DENV) is a pathogen with a high impact on human health. It replicates in a wide range of cells involved in the immune response. To efficiently infect humans, DENV must evade or inhibit fundamental elements of the innate immune system, namely the type I interferon response. DENV circumv...

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Bibliographic Details
Main Authors: Sebastian Aguirre, Ana M Maestre, Sarah Pagni, Jenish R Patel, Timothy Savage, Delia Gutman, Kevin Maringer, Dabeiba Bernal-Rubio, Reed S Shabman, Viviana Simon, Juan R Rodriguez-Madoz, Lubbertus C F Mulder, Glen N Barber, Ana Fernandez-Sesma
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Pathogens
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23055924/pdf/?tool=EBI

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23055924/pdf/?tool=EBI

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