Identification of a novel human LAP1 isoform that is regulated by protein phosphorylation.

Lamina associated polypeptide 1 (LAP1) is an integral protein of the inner nuclear membrane that is ubiquitously expressed. LAP1 binds to lamins and chromatin, probably contributing to the maintenance of the nuclear envelope architecture. Moreover, LAP1 also interacts with torsinA and emerin, protei...

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Bibliographic Details
Main Authors: Mariana Santos, Sara C Domingues, Patrícia Costa, Thorsten Muller, Sara Galozzi, Katrin Marcus, Edgar F da Cruz e Silva, Odete A da Cruz e Silva, Sandra Rebelo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0113732