Co-Administration of the Traditional Medicines Hachimi-Jio-Gan and Hochu-Ekki-To Can Reverse Busulfan-Induced Aspermatogenesis

Co-Administration of the Traditional Medicines Hachimi-Jio-Gan and Hochu-Ekki-To Can Reverse Busulfan-Induced Aspermatogenesis

Busulfan is used as a chemotherapeutic drug to treat childhood and adult chronic myelogenous leukemia, and as an immunosuppressive agent before bone marrow transplantation. A key side effect of busulfan is the alteration of male reproductive function. Infertility caused by anti-cancer treatments has...

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Bibliographic Details
Main Authors: Ning Qu, Miyuki Kuramasu, Kenta Nagahori, Yuki Ogawa, Shogo Hayashi, Yoshie Hirayanagi, Hayato Terayama, Kaori Suyama, Kou Sakabe, Masahiro Itoh
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:International Journal of Molecular Sciences
Subjects:
anti-cancer treatment
aspermatogenesis
testicular immunology
oriental medicine
co-administration
Online Access:https://www.mdpi.com/1422-0067/21/5/1716

Internet

https://www.mdpi.com/1422-0067/21/5/1716

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