Different effects of the probe summarization algorithms PLIER and RMA on high-level analysis of Affymetrix exon arrays

<p>Abstract</p> <p>Background</p> <p>Alternative splicing is an important mechanism that increases protein diversity and functionality in higher eukaryotes. Affymetrix exon arrays are a commercialized platform used to detect alternative splicing on a genome-wide scale....

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Bibliographic Details
Main Authors: Chen Yuchen, He Fei, Qu Yi
Format: Article
Language:English
Published: BMC 2010-04-01
Series:BMC Bioinformatics
Online Access:http://www.biomedcentral.com/1471-2105/11/211