Acid-sensing ion channels expression, identity and role in the excitability of the cochlear afferent neurons

Acid-sensing ion channels (ASICs) are activated by an increase in the extracellular proton concentration. There are four genes (ASIC1-4) that encode six subunits, and they are involved in diverse neuronal functions, such as mechanosensation, learning and memory, nociception, and modulation of retina...

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Bibliographic Details
Main Authors: Antonia eGonzález-Garrido, Rosario eVega, Francisco eMercado, Ivan eLópez, Enrique eSoto
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-12-01
Series:Frontiers in Cellular Neuroscience
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Online Access:http://journal.frontiersin.org/Journal/10.3389/fncel.2015.00483/full