Vascular angiotensin II type 2 receptor attenuates atherosclerosis via a kinin/NO-dependent mechanism

Vascular angiotensin II type 2 receptor attenuates atherosclerosis via a kinin/NO-dependent mechanism

Introduction: The angiotensin II (Ang II) type 1 receptor exerts pro-atherogenic action by augmenting oxidative stress, whereas the Ang II type 2 receptor (AT 2 )-mediated effect on atherosclerosis remains controversial. Materials and methods: AT 2 transgenic (AT 2 -Tg) mice, which overexpress AT 2...

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Bibliographic Details
Main Authors: Hiroki Takata, Hiroyuki Yamada, Hiroyuki Kawahito, Sou Kishida, Daisuke Irie, Taku Kato, Noriyuki Wakana, Sonoko Miyagawa, Kensuke Fukui, Hiroaki Matsubara
Format: Article
Language:English
Published: Hindawi - SAGE Publishing 2015-06-01
Series:Journal of the Renin-Angiotensin-Aldosterone System
Online Access:https://doi.org/10.1177/1470320313491794

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https://doi.org/10.1177/1470320313491794

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