The characterization of microRNA-mediated gene regulation as impacted by both target site location and seed match type.

MicroRNAs (miRNAs) are small RNA molecules that play important roles in gene regulation and translational repression. The mechanisms that facilitate miRNA target binding and recognition have been extensively studied in recent years. However, it is still not well known how the miRNA regulation is aff...

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Bibliographic Details
Main Authors: Wenlong Xu, Zixing Wang, Yin Liu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4169588?pdf=render