Definitive chemoradiotherapy with low-dose continuous 5-fluorouracil reduces hematological toxicity without compromising survival in esophageal squamous cell carcinoma patients

Definitive chemoradiotherapy with low-dose continuous 5-fluorouracil reduces hematological toxicity without compromising survival in esophageal squamous cell carcinoma patients

Background and purpose: To compare chemoradiotherapy (CRT) with low-dose continuous 5-fluorouracil (5FU) to CRT with 5FU+cisplatin (CDDP) for esophageal squamous cell carcinoma (ESCC) in a retrospective cohort study. Methods and materials: We reviewed the cases of Stage I–IV ESCC patients who underw...

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Bibliographic Details
Main Authors: Hirotake Saito, Atsushi Ohta, Eisuke Abe, Motoki Kaidu, Miki Shioi, Toshimichi Nakano, Tomoya Oshikane, Kensuke Tanaka, Katsuya Maruyama, Naotaka Kushima, Satoshi Tanabe, Satoru Utsunomiya, Ryuta Sasamoto, Hidefumi Aoyama
Format: Article
Language:English
Published: Elsevier 2018-02-01
Series:Clinical and Translational Radiation Oncology
Subjects:
Esophageal cancer
Chemoradiotherapy
5-Fluorouracil
Cisplatin
Hematological toxicity
Online Access:http://www.sciencedirect.com/science/article/pii/S2405630817300800

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http://www.sciencedirect.com/science/article/pii/S2405630817300800

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