Understanding the biology of bone sarcoma from early initiating events through late events in metastasis and disease progression.

The two most common primary bone malignancies, osteosarcoma and Ewing sarcoma, are both aggressive, highly metastatic cancers that most often strike teens, though both can be found in younger children and adults. Despite distinct origins and pathogenesis, both diseases share several mechanisms of p...

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Bibliographic Details
Main Authors: Limin eZhu, Madonna M. McManus, Dennis P. M. Hughes
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-09-01
Series:Frontiers in Oncology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fonc.2013.00230/full