Using amino acid physicochemical distance transformation for fast protein remote homology detection.

Protein remote homology detection is one of the most important problems in bioinformatics. Discriminative methods such as support vector machines (SVM) have shown superior performance. However, the performance of SVM-based methods depends on the vector representations of the protein sequences. Prior...

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Bibliographic Details
Main Authors: Bin Liu, Xiaolong Wang, Qingcai Chen, Qiwen Dong, Xun Lan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3460876?pdf=render