Extensive neuroprotection by choroid plexus transplants in excitotoxin lesioned monkeys

Extensive neuroprotection by choroid plexus transplants in excitotoxin lesioned monkeys

Huntington's disease (HD) results from degeneration of striatal neurons. Choroid plexus (CP) cells secrete neurotrophic factors, and CP transplants are neuroprotective in rat models of HD. To determine if similar neuroprotective effects could be obtained in primates, porcine CP was encapsulated...

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Bibliographic Details
Main Authors: Dwaine F. Emerich, Christopher G. Thanos, Moses Goddard, Stephen J.M. Skinner, Marilyn S. Geany, William J. Bell, Briannan Bintz, Patricia Schneider, Yaping Chu, Rangasamy Suresh Babu, Cesario V. Borlongan, Kim Boekelheide, Susan Hall, Bronwyn Bryant, Jeffrey H. Kordower
Format: Article
Language:English
Published: Elsevier 2006-08-01
Series:Neurobiology of Disease
Subjects:
Choroid plexus
CNS transplantation
Alginate
Encapsulation
Neuroprotection
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996106000891

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http://www.sciencedirect.com/science/article/pii/S0969996106000891

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