Melatonin enhances radiofrequency-induced NK antitumor immunity, causing cancer metabolism reprogramming and inhibition of multiple pulmonary tumor development

Abstract Surgery is the common treatment for early lung cancer with multiple pulmonary nodules, but it is often accompanied by the problem of significant malignancy of other nodules in non-therapeutic areas. In this study, we found that a combined treatment of local radiofrequency ablation (RFA) and...

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Bibliographic Details
Main Authors: Ming Li, Bingjie Hao, Menghuan Zhang, Russel J. Reiter, Shumeng Lin, Tiansheng Zheng, Xiangyun Chen, Yanbei Ren, Liduo Yue, Baigenzhin Abay, Guojie Chen, Xiao Xu, Yufeng Shi, Lihong Fan
Format: Article
Language:English
Published: Nature Publishing Group 2021-09-01
Series:Signal Transduction and Targeted Therapy
Online Access:https://doi.org/10.1038/s41392-021-00745-7