Silymarin inhibits cisplatin-mediated apoptosis via inhibition of hydrogen peroxide and hydroxyl radical generation

Silymarin inhibits cisplatin-mediated apoptosis via inhibition of hydrogen peroxide and hydroxyl radical generation

Cisplatin mediated nephrotoxicity has been continuously reported and recognized as a major obstacle for cisplatinbased chemotherapy. The present study aimed to demonstrate the potential use of silymarin, an extract from the seed of Silybum marianum L., as a combination therapy with cisplatin. Prev...

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Bibliographic Details
Main Authors: Angkana Tantituvanont, Pacharaporn Jiamchaisri, Preedakorn Chunhacha, Kanittha Pongjit, Chuanpit Ninsontia, Kulwara Meksawan, Boonchoo Sritularak, Pithi Chanvorachote
Format: Article
Language:English
Published: Prince of Songkla University 2015-04-01
Series:Songklanakarin Journal of Science and Technology (SJST)
Subjects:
silymarin
cisplatin
renal epithelial cell
nephroprotective
ROS
Online Access:http://rdo.psu.ac.th/sjstweb/journal/37-2/37-2-6.pdf

Internet

http://rdo.psu.ac.th/sjstweb/journal/37-2/37-2-6.pdf

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