Meta-analysis of gene expression disease signatures in colonic biopsy tissue from patients with ulcerative colitis

Meta-analysis of gene expression disease signatures in colonic biopsy tissue from patients with ulcerative colitis

Abstract Publicly available ulcerative colitis (UC) gene expression datasets from observational studies and clinical trials include inherently heterogeneous disease characteristics and methodology. We used meta-analysis to identify a robust UC gene signature from inflamed biopsies. Eight gene expres...

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Bibliographic Details
Main Authors: Bryan Linggi, Vipul Jairath, Guangyong Zou, Lisa M. Shackelton, Dermot P. B. McGovern, Azucena Salas, Bram Verstockt, Mark S. Silverberg, Shadi Nayeri, Brian G. Feagan, Niels Vande Casteele
Format: Article
Language:English
Published: Nature Publishing Group 2021-09-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-97366-5

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https://doi.org/10.1038/s41598-021-97366-5

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