Stabilizing ER Ca2+ channel function as an early preventative strategy for Alzheimer's disease.

Alzheimer's disease (AD) is a devastating neurodegenerative condition with no known cure. While current therapies target late-stage amyloid formation and cholinergic tone, to date, these strategies have proven ineffective at preventing disease progression. The reasons for this may be varied, an...

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Bibliographic Details
Main Authors: Shreaya Chakroborty, Clark Briggs, Megan B Miller, Ivan Goussakov, Corinne Schneider, Joyce Kim, Jaime Wicks, Jill C Richardson, Vincent Conklin, Benjamin G Cameransi, Grace E Stutzmann
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3528716?pdf=render