Disease Severity, Fever, Age, and Sex Correlate With SARS-CoV-2 Neutralizing Antibody Responses

Disease Severity, Fever, Age, and Sex Correlate With SARS-CoV-2 Neutralizing Antibody Responses

Clinical trials on the use of COVID-19 convalescent plasma remain inconclusive. While data on safety is increasingly available, evidence for efficacy is still sparse. Subgroup analyses hint to a dose-response relationship between convalescent plasma neutralizing antibody levels and mortality. In par...

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Bibliographic Details
Main Authors: Stephan Schlickeiser, Tatjana Schwarz, Sophie Steiner, Kirsten Wittke, Nabeel Al Besher, Oliver Meyer, Ulrich Kalus, Axel Pruß, Florian Kurth, Thomas Zoller, Martin Witzenrath, Leif Erik Sander, Marcel A. Müller, Carmen Scheibenbogen, Hans-Dieter Volk, Christian Drosten, Victor M. Corman, Leif G. Hanitsch
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Immunology
Subjects:
COVID-19
SARS-CoV-2
immunodeficiency
antibody deficiency
coronavirus disease 2019
convalescent plasma
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2020.628971/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2020.628971/full

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