High-Throughput Metabolomics Evaluate the Efficacy of Total Lignans From Acanthophanax Senticosus Stem Against Ovariectomized Osteoporosis Rat

High-Throughput Metabolomics Evaluate the Efficacy of Total Lignans From Acanthophanax Senticosus Stem Against Ovariectomized Osteoporosis Rat

Postmenopausal osteoporosis (PMOP) is a common clinical illness in postmenopausal women, but there is no effective drug at present. Metabolomics approach was used to explore the potential biomarkers of PMOP and evaluate the efficacy and therapeutic targets of total lignans in the stem of Acanthophan...

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Bibliographic Details
Main Authors: Ai-hua Zhang, Zhi-ming Ma, Hui Sun, Ying Zhang, Jian-hua Liu, Fang-fang Wu, Xi-jun Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-05-01
Series:Frontiers in Pharmacology
Subjects:
metabolomics
biomarker
metabolic pathway
lignans
herbal medicine
efficacy
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2019.00553/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2019.00553/full

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