Concise Review: Regulation of Self‐Renewal in Normal and Malignant Hematopoietic Stem Cells by Krüppel‐Like Factor 4
Abstract Pluripotent and tissue‐specific stem cells, such as blood‐forming stem cells, are maintained through a balance of quiescence, self‐renewal, and differentiation. Self‐renewal is a specialized cell division that generates daughter cells with the same features as the parental stem cell. Althou...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Wiley
2019-06-01
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Series: | Stem Cells Translational Medicine |
Subjects: | |
Online Access: | https://doi.org/10.1002/sctm.18-0249 |