Concise Review: Regulation of Self‐Renewal in Normal and Malignant Hematopoietic Stem Cells by Krüppel‐Like Factor 4

Abstract Pluripotent and tissue‐specific stem cells, such as blood‐forming stem cells, are maintained through a balance of quiescence, self‐renewal, and differentiation. Self‐renewal is a specialized cell division that generates daughter cells with the same features as the parental stem cell. Althou...

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Bibliographic Details
Main Authors: Chun S. Park, Andrew Lewis, Taylor Chen, Daniel Lacorazza
Format: Article
Language:English
Published: Wiley 2019-06-01
Series:Stem Cells Translational Medicine
Subjects:
Online Access:https://doi.org/10.1002/sctm.18-0249