Orexin 1 receptor antagonists in compulsive behaviour and anxiety: possible therapeutic use.

Fifteen years after the discovery of hypocretin/orexin a large body of evidence has been collected supporting its critical role in the modulation of several regulatory physiological functions. While reduced levels of hypocretin/orexin were early on associated with narcolepsy, increased levels have b...

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Bibliographic Details
Main Authors: Emilio eMerlo-Pich, Sergio eMelotto
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-02-01
Series:Frontiers in Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnins.2014.00026/full